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Glucosamine supplements 'may cut heart risk' – BBC News

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Glucosamine supplements, better known as a remedy for joint pain, may lower a person’s risk of cardiovascular disease (CVD), research suggests.

The findings in the British Medical Journal (BMJ) come from nearly half a million people in the UK.

Almost one in five of the 466,039 participants said they took glucosamine.

Users were less likely to develop heart and artery diseases or stroke, or die from these conditions.

The results suggest a possible benefit, but more and longer studies are needed.

It could be that users are generally more healthy, rather than glucosamine having a direct effect, experts caution.

What is glucosamine?

Glucosamine is a naturally occurring compound found in joint cartilage.

The body can make its own glucosamine, but supplements are sometimes used by people looking to relieve pain and symptoms of osteoarthritis and other joint disorders.

Most glucosamine supplements are sold in pharmacies and health food shops in the UK as a “food supplement” and not a medicine. They are checked for food safety to ensure they won’t do you any harm, but they are not checked for quality or quantity of the “active” ingredient.

The active ingredient can be made synthetically or derived from the shells of shellfish.

Does it work?

The evidence supporting the effectiveness of glucosamine for joint pain is mixed and very limited. Guidelines for the NHS do not recommend it for osteoarthritis.

The new suggested link to a lower risk of cardiovascular disease needs more research. The BMJ study was observational – it can’t establish cause. And it did not include detailed information on glucosamine dose or duration of use.

Glucosamine was associated with a 9%-22% lower risk of CVD death, coronary heart disease and stroke, compared to non-use over the 10 years of the study.

The researchers believe the supplement may have an anti-inflammatory effect, which could explain the suggested benefit, but more investigations are needed.

Is it safe?

Studies on the safety of glucosamine are limited.

People with an allergy to shellfish should not take it, nor should women who are pregnant or breastfeeding.

Glucosamine should be avoided by people taking warfarin, as it may affect blood clotting.

It may also decrease the effectiveness of some anti-cancer drugs, say experts.

Like any supplement or medication, it can cause side-effects in some individuals.

What do experts think of the findings?

Prof Naveed Sattar, from the University of Glasgow, said: “Only a trial can determine whether there is any truth to the lower observed risk. Observational studies can only ever generate new ideas to test.

“Many other supplements have not proven benefits in trials even when observational data suggested there may be health benefits. Some supplements have even been shown to cause harm in trials. So, for now, I would not rush to buy glucosamine to lessen my heart risks when there are many other cost-effective proven ways to do so.”

Dr Sonya Babu-Narayan, from the British Heart Foundation, said: “One in four people in the UK still die from heart and circulatory disease. We urgently need to fund research that could result in improved prevention, diagnosis and treatment.

“If a well-known and widely available supplement like glucosamine could help prevent heart and circulatory diseases, including heart attack and stroke, it is an avenue of research worth exploring.

“Meanwhile, an important way to reduce your risk is to maintain a healthy lifestyle and – when relevant – take medications as recommended to you by your doctor.”

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Collagen supplement use growing in popularity, improves skin, hair and nails – WXYZ

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There are so many options when a person goes into a supplement store, from vitamins to minerals and protein powders and more.

The latest one to grow in popularity? Collagen.

At Supplement Giant, owner Adam Watts says collagen powder is a popular product.

“Collagen is actually the most abundant amount of protein in our body,” Watts said.

Collagen represents 30 percent of a human body’s protein content.

“It’s found in animal bones ligaments and tendons again not traditionally part of our diet anymore,” he said.

Most brands sell collagen as a great supplement to take to improve a person’s hair, skin, fingernails, and bone and joint health.

“If you have a deficiency of collagen in your skin it can decrease you skin health which can cause stretch marks, dark spots, infections,” Watts said.

He suggests people age 30 and older take a collagen supplement.

“After the age of 30, collagen decreases by 1 percent, so by the time you’re 50, you’ve lost 20 percent of your collagen,” he said. “If you have injuries, collagen is going to help and repair tissue.”

Registered Dietician Jessica Crandall Snyder said she recommends food as medicine, not supplements.

“Being active on a daily basis you are actually helping to re-synthesize your collagen,” she said, “So supplemental sources from protein powders may not be the way for you to get adequate nutrition.”

While Adam Watts sells collagen powder at whole sale, other stores start the product at $25 per container.

But eggs, wild salmon, tomatoes, pumpkin and chia seeds are affordable foods that aid in collagen production.

The experts say collagen powder works, but make sure it’s not your main source of protein.

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CA Permit Sale of Hemp-Derived CBD in Foods & Supplements – The National Law Review

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California Assembly Bill 228 would expressly permit the retail sale of hemp-derived CBD in foods and supplements in California, notwithstanding the Food and Drug Administration’s position to the contrary. On Thursday, May 16, 2019, AB-228 passed through the State Assembly’s Appropriations Committee with a unanimous 18-0 approval. The Bill, sponsored by Assembly Member Cecilia Aguiar-Curry (District 4), moves to the House floor where a two thirds vote is required for it to continue on to the Senate for approval. 

AB-228 is intended to address the guidance offered by the California Department of Public Health (CDPH) in July 2018, which prohibits hemp-derived CBD from being added to foods. The CDPH’s release provides: 

California incorporates federal law regarding food additives, dietary use products, food labeling, and good manufacturing practices for food… Currently, the United States Food and Drug Administration (FDA) has concluded that it is a prohibited act to introduce or deliver for introduction into interstate commerce any food (including any animal food or feed) to which tetrahydrocannabinol (THC) or CBD has been added. This is regardless of the source of CBD – derived from industrial hemp or cannabis. 

While manufacturing and retail sales of marijuana-derived CBD products are permitted in accordance with California’s cannabis regulations, hemp-derived CBD remains unapproved for use as a food ingredient, food additive or dietary supplement. 

The City of Los Angeles took a similar position when its Department of Public Health, Environmental Health, which regulates food operators, issued the following guidance: “use of industrial hemp derived products in food will be considered adulterated and cited by DPH-EH as a violation resulting in a deduction of two (2) points on the official inspection report.” The Los Angeles guidance becomes effective on July 1, 2019. 

In response to the FDA’s position, California would join multiple states, including Colorado and Illinois, that have released policies allowing hemp-derived CBD in foods. AB-228 provides that “the sale of food or beverages that include hemp or cannabinoids, extracts, or derivatives from industrial hemp shall not be restricted or prohibited based solely on the inclusion of industrial hemp or cannabinoids, extracts, or derivatives from industrial hemp. 

Though legalization at the state level does not preclude FDA enforcement, AB-228 would provide California defendants with an affirmative defense in civil court to unlawful adulterant allegations regarding CBD products. AB-228 also would allow hemp-derived CBD product sales by licensed cannabis businesses and declare that industrial hemp and its derivatives are an agricultural product. 

If the California House of Representatives passes AB-228, it will move on to the Senate where it must receive support by an assigned Senate committee before being placed on the Senate floor for a vote. If approved by the Senate, AB-228 will be delivered to Governor Newsom for final approval.

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Warning: Avoid dietary supplements from these 12 companies – ActionNewsJax.com

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In the quest to be healthy, dietary supplements continue to be a popular option with some people but the U.S. Food and Drug Administration’s recent warnings to companies hawking such products should cause potential customers to proceed with caution.

The agency recently sent out warnings to several companies that it said did not adhere to government guidelines on dietary supplement claims and their purported benefits.

FDA warns 12 companies over dietary supplement claims

Three of the companies ran afoul of the law by making claims about phenibut, which is sometimes marketed as a sleep aid. According to the FDA, phenibut does not meet the statutory definition of a dietary ingredient.

The FDA also issued nine warning letters to companies marketing DMHA (Dimethylhexylamine or 2-aminoisoheptane) as an ingredient in numerous dietary supplements.

In April 2019, the FDA determined that DMHA, which is often marketed for weight loss and sports performance, is either a “new dietary ingredient” for which the agency has yet to receive the mandatory New Dietary Ingredient notification or is “an unsafe food additive.”

The violations ultimately mean that American consumers may be buying and using products that are not approved for consumption. It also means the remedial claims of the products are as of yet unproven.

On the FDA’s website, a dietary supplement is defined as “a dietary ingredient as a vitamin; mineral; herb or other botanical; amino acid; dietary substance for use by man to supplement the diet by increasing the total dietary intake; or a concentrate, metabolite, constituent, extract, or combination of the preceding substances.”

But then there is this major distinction: “Unlike drugs, supplements are not intended to treat, diagnose, prevent, or cure diseases. That means supplements should not make claims, such as ‘reduces pain’ or ‘treats heart disease.’ Claims like these can only legitimately be made for drugs, not dietary supplements.”

Here are the FDA warning letters to the 12 companies

Warning Letters (DMHA):

Warning Letters (Phenibut):


Do you use dietary supplements? If so, do these warnings concern you at all? Let us know in the comments below!

The post Warning: Avoid dietary supplements from these 12 companies appeared first on Clark Howard.

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